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Beilstein J. Org. Chem. 2018, 14, 194–202, doi:10.3762/bjoc.14.14
Graphical Abstract
Figure 1: Selected indolo[3,2-b]quinolines (quindolines) with biological activity.
Scheme 1: Selected starting materials for the construction of the quindoline system.
Scheme 2: Synthesis of condensed pyridines mediated by a σH-adduct.
Scheme 3: Formation of condensed isoxazole derivatives.
Scheme 4: Reaction of unprotected indole ester 1c with 4-chloronitrobenzene.
Scheme 5: A plausible mechanism for the formation of 11-(phenylsulfonyl)indolo[3,2-b]quinolines.